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<p>List of Contributors ix</p> <p>Preface xvi</p> <p>Foreword xvii</p> <p><b>Part 1: Gastroesophageal Cancer<br /></b><i>Edited by Richard Sampliner</i></p> <p>1 Epidemiology of Gastroesophageal Cancer 3<br /><i>Evan S. Dellon & Nicholas J. Shaheen</i></p> <p>2 Factors involved in Carcinogenesis and Prevention 14<br /><i>Mark R. Anderson & Janusz Jankowski</i></p> <p>3 Molecular Biology of Gastroesophageal Cancers: the Role of Mutational Analysis in Prognosis 21<br /><i>Matthew Lovell, Chetan Bhan, Janusz Jankowski & Stuart McDonald</i></p> <p>4 Esophageal Adenocarcinoma 31<br /><i>Edited by Kenneth K. Wang</i></p> <p>5 Squamous Cancer of the Esophagus 114<br /><i>Edited by Hugh Barr</i></p> <p>6 Diffuse Gastric Cancer 146<br /><i>Edited by Ilfet Songun & Cornelius van de Velde</i></p> <p>7 Intestinal Gastric Cancer 177<br /><i>Edited by Benjamin C.Y. Wong</i></p> <p>8 Small Bowel Tumors 189<br /><i>Edited by Nadir Arber</i></p> <p>9 Sarcoma and Gastrointestinal Stromal Tumors 227<br /><i>Edited by Markku Miettinen</i></p> <p>10 Rare Tumors of the Abdomen 259<br /><i>Edited by Anil R. Prasad</i></p> <p><b>Part 2: Colorectal Cancer<br /></b><i>Edited by David Kerr</i></p> <p>11 Epidemiology and Prevention of Colorectal Cancer 293<br /><i>Paul Moayyedi</i></p> <p>12 The Molecular Pathology of Sporadic and Hereditary Colorectal Cancer 305<br /><i>Massimo Pignatelli, Nahida Banu & Zsombor Melegh</i></p> <p>13 Screening for Colorectal Cancer 317<br /><i>Robert J.C. Steele</i></p> <p>14 Cancer of the Colon and Rectum 325<br /><i>Edited by Rachel S. Midgley</i></p> <p>15 Rare Cancers 374<br /><i>Edited by Colin McArdle</i></p> <p><b>Part 3: Hepatobiliary Cancer<br /></b><i>Edited by Yuman Fong</i></p> <p>16 Epidemiology of Hepatocellular Carcinoma 411<br /><i>Hashem B. El-Serag, Donna L. White & Zhannat Nurgalieva</i></p> <p>17 Factors involved in Carcinogenesis and Prevention in Hepatobiliary Cancer 421<br /><i>Paula Ghaneh, William Greenhalf & John P. Neoptolemos</i></p> <p>18 Molecular Biology of Hepatobiliary Cancer 433<br /><i>Knut Ketterer & Helmut Friess</i></p> <p>19 Primary Liver Cancer 441<br /><i>Edited by Charlie Pan & Theodore Lawrence</i></p> <p>20 Metastatic Liver Cancer 469<br /><i>Edited by Yuman Fong</i></p> <p>21 Primary Pancreatic Adenocarcinoma 498<br /><i>Edited by Christopher L. Wolfgang</i></p> <p>22 Cholangiocarcinoma 543<br /><i>Edited by Ravi S. Chari</i></p> <p>23 Neuroendocrine Tumors 564<br /><i>Edited by Ursula Plöckinger</i></p> <p>24 Rare Tumors of the Liver 669<br /><i>Shantanu Bhattacharjya, Zahir Soonawalla, Rachel R. Phillips & Peter J. Friend</i></p> <p>25 Cystic Neoplasms of the Pancreas 688<br /><i>Edited by Peter J. Allen</i></p> <p>Index 711</p>

"If multiple authorship is a mark of quality, this book is a must-read. With 189 authors covering the oncology of the gastrointestinal tract from the esophagus to the anus, as well as the pancreas, hepatobiliary system, and peritoneum, the book is comprehensive indeed." (<i>The New England Journal of Medicine</i>, March 2009) <p>“Written by the leading international experts in the field, it sets the standard in clinical practice.” (<i>Doody's Reviews</i>)<br /><br />"The book is intended for multidisciplinary meetings dealing with tumors of the digestive system, a worthy objective. This is great book that will hopefully set a standard for a new type of book that reflects today's multidisciplinary approach to gastrointestinal tumors."  (Patrick Mosler, MD, PhD, @Doody's Review Service)</p>

Janusz Jankowski<br /> <p>MD, PhD, FRCP, FACG<br /> </p> <p>Consultant Gastroenterologist, Digestive Diseases Centre UHL Trust, Leicester, UK<br /> </p> <p>James Black Senior Fellow and Professor, University of Oxford, UK<br /> </p> <p>Fellow and Professor, Cancer Research UK and Queen Mary University of London, UK<br /> </p> <p><br /> Richard Sampliner<br /> </p> <p>MD<br /> </p> <p>Professor of Medicine, University of Arizona College of Medicine, USA<br /> </p> <p>Chief of Gastroenterology, Southern Arizona VA Health Care System, USA<br /> </p> <p><br /> David Kerr<br /> </p> <p>CBE, MA, MD, DSc, FRCP, FMedSci<br /> </p> <p>Rhodes Professor of Cancer Therapeutics and Clinical Pharmacology, University of Oxford, UK<br /> </p> <p>Head of Department of Clinical Pharmacology, University of Oxford, UK<br /> </p> <p><br /> Yuman Fong<br /> </p> <p>MD<br /> </p> <p>Murray F. Brennan Chair in Surgery, Memorial Sloan-Kettering Cancer Center, New York, USA<br /> </p> <p>Professor of Surgery, Weill Cornell Medical Center, New York, USA<br /> </p>

<i>Gastrointestinal Oncology: A Critical Multidisciplinary Team Approach</i> is the first evidence-based reference text designed for the multidisciplinary team of medical professionals involved in the investigation, diagnosis, and management of patients with gastrointestinal cancer. Written and edited by leading international experts in the field it sets the standard in clinical practice for dealing with esophageal, gastric, intestinal, colonic, hepatobiliary, pancreatic, and other GI tumors.<br /> <p>The book is divided into twenty-five clinical chapters each addressing the specific cancers affecting the gastrointestinal tract. Each chapter is written by a team of authors, with each contributor specially chosen to represent a different role in the MDT. This multidisciplinary team approach reflects the current care of GI cancer patients and enables clinical decision making and patient management. All the chapters have been tried and tested in MDT meetings in leading cancer centers around the world.<br /> </p> <p><i>Gastrointestinal Oncology: A Critical Multidisciplinary Team Approach</i> provides in-depth evidence-based knowledge and is well illustrated throughout with color photographs, line drawings, and diagrams. This authoritative and practical resource is an essential reference for the entire MDT including gastroenterologists, hepatologists, GI surgeons, medical oncologists, radiation therapists, interventional radiologists, pathologists, specialist nurses, and clinical scientists.</p>

“The editors of ‘Gastrointestinal oncology: a critical multi-disciplinary approach’ are to be congratulated on bringing together an exceptional array of international experts as authors of this textbook. Set out in three sections – Gastroesophageal, colorectal and hepatobiliary – and 25 chapters it is an encyclopaedia for professionals involved in all aspects of these diseases. Clinicians who wish to find out more about the epidemiology, risk factors, diagnosis, treatment and palliation of gastrointestinal tumours, common or rare, will now be able to turn to a single authoritative textbook.”<br /> –<b>Professor Mike Richards</b>, National Cancer Director for England

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